Dr. Lee attended Yale University, receiving his undergraduate degree in psychology in 1978. He continued his studies at the University of Illinois/Chicago, earning his PhD in Physiology and Biophysics in 1983 and MD in 1988. He trained as a resident in neuropathology in Boston at Massachusetts General Hospital, Harvard Medical School. Then, in 1992, Dr. Lee went to Loyola University Medical Center, where he held many leadership positions, including Chairman of Pathology, Vice-President of Loyola University Medical Center and Dean of the Stritch School of Medicine. 

Dr. Lee was recruited to NorthShore University Health System in 2013 and established a Brain Bank for neurodegenerative disease and traumatic brain injury. He is a member of the American Association for the Advancement of Science, College of American Pathology and the American Association of Neuropathologists (AANP). Dr. Lee has published well over 100 articles and book chapters and has written and lectured on topics including neuropathology and clinical drug development for Alzheimer’s disease, traumatic brain injury (TBI) and chronic traumatic encephalopathy (CTE).